Downloads

• Current Release - PICKLE 3.3
  • Human PICKLE 3.3»
  • Mouse PICKLE 3.3»
• Archived Releases
• PICKLE 3.2»
• Human PICKLE 3.2»
• Mouse PICKLE 3.2»
• PICKLE 3.1»
• Human PICKLE 3.1»
• Mouse PICKLE 3.1»
• PICKLE 2.6»
• PICKLE 2.5»
• PICKLE 2.4»
• PICKLE 2.3»
• PICKLE 2.2»
• PICKLE 2.1»
• PICKLE 1.1»

Current Release - PICKLE 3.3 (released on Oct 1, 2021)

 

Human PICKLE

Ontological network in OWL format (based on UniProtKB version 2021_03, GenBank 2021-06-24, ENA release 143, RefSeq 2021-07-08 and Ensembl release 104)

• Download

PPI network (based on IntAct release 239, BioGRID release 4.4.198 and HPRD release 9)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 16420, Interactions: 218025)
  • Standard (UniProt IDs: 16828, Interactions: 228444)
  • Unfiltered (UniProt IDs: 17946, Interactions: 585792)
  • Full (UniProt IDs: 18038, Interactions: 602125)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    16233, Interactions: 218891)
  • Standard (Gene IDs:    16645, Interactions: 229416)
  • Unfiltered (Gene IDs:    17672, Interactions: 590249)
  • Full (Gene IDs:    17765, Interactions: 607020)

 

Mouse PICKLE

Ontological network in OWL format (based on UniProtKB version 2020_03, GenBank 2020-06-25, ENA release 143, RefSeq 2021-06-25 and Ensembl release 104)

• Download

Orthologues List (based on MGI Vertebrate Homology release 6.17/2020-07-20 and Ensembl release 104)

• Download (15130 orthologue pairs)

PPI network (based on IntAct release 239 and BioGRID release 4.4.198)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs:   8741, Interactions: 19351) | EbO mouse Cross-checked (Default) (UniProt IDs:   7026, Interactions: 18081)
  • Standard (UniProt IDs:   8971, Interactions: 20365) | EbO mouse Standard (UniProt IDs:   7195, Interactions: 19050)
  • Unfiltered (UniProt IDs: 17498, Interactions: 93546) | EbO mouse Unifltered (UniProt IDs: 12213, Interactions: 90073)
  • Full (UniProt IDs: 17567, Interactions: 94476)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:      8435, Interactions: 18702) | EbO mouse Cross-checked (Default) (Gene IDs:      6538, Interactions: 17061)
  • Standard (Gene IDs:      8669, Interactions: 19715) | EbO mouse Standard (Gene IDs:      6724, Interactions: 18022)
  • Unfiltered (Gene IDs:    17088, Interactions: 92098) | EbO mouse Unfiltered (Gene IDs:     11503, Interactions: 87275)
  • Full (Gene IDs:    17156, Interactions: 93180)

Archived Releases

Current Release - PICKLE 3.2 (released on Mar 1, 2021)

 

Human PICKLE

Ontological network in OWL format (based on UniProtKB version 2020_06, GenBank 2020-12-14, ENA release 143, RefSeq 2020-12-14 and Ensembl release 102)

• Download

PPI network (based on IntAct release 236/2020-12-11, BioGRID release 4.2.192/2020-11-25 and HPRD release 9)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 16384, Interactions: 214446)
  • Standard (UniProt IDs: 16803, Interactions: 224842)
  • Unfiltered (UniProt IDs: 17915, Interactions: 528710)
  • Full (UniProt IDs: 17992, Interactions: 541901)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    16197, Interactions: 215372)
  • Standard (Gene IDs:    16619, Interactions: 225867)
  • Unfiltered (Gene IDs:    17640, Interactions: 532372)
  • Full (Gene IDs:    17716, Interactions: 546015)

 

Mouse PICKLE

Ontological network in OWL format (based on UniProtKB version 2020_06, GenBank 2020-12-14, ENA release 143, RefSeq 2020-12-14 and Ensembl release 102)

• Download

Orthologues List (based on MGI Vertebrate Homology release 6.16-01/12/2020 and Ensembl release 102)

• Download (15152 orthologue pairs)

PPI network (based on IntAct release 236/2020-12-11 and BioGRID release 4.2.192/2020-11-25)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs:   8628, Interactions: 19025) | EbO mouse Cross-checked (Default) (UniProt IDs:   6922, Interactions: 17771)
  • Standard (UniProt IDs:   8856, Interactions: 19992) | EbO mouse Standard (UniProt IDs:   7090, Interactions: 18696)
  • Unfiltered (UniProt IDs: 17636, Interactions: 93869) | EbO mouse Unifltered (UniProt IDs: 12329, Interactions: 90442)
  • Full (UniProt IDs: 17702, Interactions: 94798)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:      8317, Interactions: 18369) | EbO mouse Cross-checked (Default) (Gene IDs:      6478, Interactions: 16813)
  • Standard (Gene IDs:      8549, Interactions: 19328) | EbO mouse Standard (Gene IDs:      6661, Interactions: 17730)
  • Unfiltered (Gene IDs:    17204, Interactions: 93158) | EbO mouse Unfiltered (Gene IDs:     11640, Interactions: 88422)
  • Full (Gene IDs:    17269, Interactions: 94237)

PICKLE 3.1 (released on Aug 07, 2020)

 

Human PICKLE (equals to PICKLE 2.5)

Ontological network in OWL format (based on UniProtKB version 2019-10, GenBank 2019-11-04, ENA release 141, RefSeq 2019-11-04 and Ensembl release 98)

• Download

PPI network (based on IntAct release 227/2019-11-04, BioGRID release 3.5.178, DIP release 20170205 and HPRD release 9)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 16418, Interactions: 191113)
  • Standard (UniProt IDs: 16560, Interactions: 196511)
  • Unfiltered (UniProt IDs: 17706, Interactions: 425340)
  • Full (UniProt IDs: 17794, Interactions: 436713)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    16205, Interactions: 191755)
  • Standard (Gene IDs:    16351, Interactions: 197189)
  • Unfiltered (Gene IDs:    17423, Interactions: 428676)
  • Full (Gene IDs:    17509, Interactions: 440455)

 

Mouse PICKLE

Ontological network in OWL format (based on UniProtKB version 2019-10, GenBank 2019-12-16, ENA release 141, RefSeq 2019-12-16 and Ensembl release 98)

• Download

Orthologues List (based on MGI Vertebrate Homology, accessed 18/03/2020 and Ensembl 99)

• Download (15128 orthologue pairs)

PPI network (based on IntAct release 228/2019-11-20, BioGRID release 3.5.179 and DIP release 20170205)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs:   7842, Interactions: 16422) | EbO mouse Cross-checked (Default) (UniProt IDs:   6240, Interactions: 15224)
  • Standard (UniProt IDs:   8214, Interactions: 17912) | EbO mouse Standard (UniProt IDs:   6508, Interactions: 16614)
  • Unfiltered (UniProt IDs: 16140, Interactions: 63912) | EbO mouse Unifltered (UniProt IDs: 11326, Interactions: 61367)
  • Full (UniProt IDs: 16203, Interactions: 64805)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:      7539, Interactions: 15775) | EbO mouse Cross-checked (Default) (Gene IDs:      5867, Interactions: 14321)
  • Standard (Gene IDs:      7906, Interactions: 17219) | EbO mouse Standard (Gene IDs:      6149, Interactions: 15660)
  • Unfiltered (Gene IDs:    15719, Interactions: 63353) | EbO mouse Unfiltered (Gene IDs:     10878, Interactions: 59554)
  • Full (Gene IDs:    15791, Interactions: 64935)

 

PICKLE 2.6 (released on September 30, 2020)

Ontological network in OWL format (based on UniProtKB version 2020_03, GenBank 2020-09-11, ENA release 143 and Ensembl release 100)

• Download

PPI network (based on IntAct release 234, BioGRID release 3.5.187 and HPRD release 9)

• Normalized at the UniProt level
  • Cross-checked (Default) (UniProt IDs: 16568, Interactions: 201524)
  • Standard (UniProt IDs: 16703, Interactions: 207456)
  • Unfiltered (UniProt IDs: 17824, Interactions: 475056)
  • Full (UniProt IDs: 17897, Interactions: 487524)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    16390, Interactions: 202436)
  • Standard (Gene IDs:    16527, Interactions: 208411)
  • Unfiltered (Gene IDs:    17543, Interactions: 479347)
  • Full (Gene IDs:    17616, Interactions: 492221)

Note: Since this release, PICKLE integrates every database included by IntAct.

 

PICKLE 2.5 (released on November 15, 2019)

Ontological network in OWL format (based on UniProtKB version 2019-10, GenBank 2019-11-04, ENA release 141, RefSeq 2019-11-04 and Ensembl release 98)

• Download

PPI network (based on IntAct release 227/2019-11-04, BioGRID release 3.5.178, DIP release 20170205 and HPRD release 9)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 16418, Interactions: 191113)
  • Standard (UniProt IDs: 16560, Interactions: 196511)
  • Unfiltered (UniProt IDs: 17706, Interactions: 425340)
  • Full (UniProt IDs: 17794, Interactions: 436713)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    16205, Interactions: 191755)
  • Standard (Gene IDs:    16351, Interactions: 197189)
  • Unfiltered (Gene IDs:    17423, Interactions: 428676)
  • Full (Gene IDs:    17509, Interactions: 440455)

 

PICKLE 2.4 (released on June 18 2019)

Ontological network in OWL format (based on UniProtKB version 2019-05, GenBank 2019-06-14, ENA release 139 and Ensembl release 96)

• Download

PPI network (based on IntAct release 224/2019-06-14, BioGRID release 3.5.173, DIP release 20170205 and HPRD release 9)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 16418, Interactions: 189693)
  • Standard (UniProt IDs: 16456, Interactions: 194346)
  • Unfiltered (UniProt IDs: 17694, Interactions: 409868)
  • Full (UniProt IDs: 17768, Interactions: 419218)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    16218, Interactions: 191510)
  • Standard (Gene IDs:    16256, Interactions: 196186)
  • Unfiltered (Gene IDs:    17437, Interactions: 413808)
  • Full (Gene IDs:    17508, Interactions: 423523)

 

PICKLE 2.3 (released on October 31 2018)

Ontological network in OWL format (based on UniProtKB version 2018_09, GenBank 2018-10-03, ENA release 137 and Ensembl release 94)

• Download

PPI network (based on IntAct release 218/2018-09-07, BioGRID release 3.5.165, DIP release 20170205 and HPRD release 9)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 15823, Interactions: 178306)
  • Standard (UniProt IDs: 15868, Interactions: 182921)
  • Unfiltered (UniProt IDs: 17300, Interactions: 367709)
  • Full (UniProt IDs: 17402, Interactions: 376681)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    15682, Interactions: 179737)
  • Standard (Gene IDs:    15727, Interactions: 184374)
  • Unfiltered (Gene IDs:    17094, Interactions: 371349)
  • Full (Gene IDs:    17193, Interactions: 380705)

 

PICKLE 2.2 (released on May 11 2018)

Ontological network in OWL format (based on UniProtKB 2017_12, GenBank release 222, ENA release 133 and Ensembl release 91)

• Download

PPI network (based on IntAct release 2017-11-06, BioGRID release 3.4.155, DIP release 20170205 and HPRD release 9)

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 15434, Interactions: 161007)
  • Standard (UniProt IDs: 15483, Interactions: 165568)
  • Unfiltered (UniProt IDs: 17064, Interactions: 334069)
  • Full (UniProt IDs: 17119, Interactions: 339791)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    15322, Interactions: 162652)
  • Standard (Gene IDs:    15371, Interactions: 167235)
  • Unfiltered (Gene IDs:    16899, Interactions: 336008)
  • Full (Gene IDs:    16954, Interactions: 342116)

 

PICKLE 2.1 (released on August 11 2017)

Ontological network in OWL format

• Download

PPI network

• Normalized at the Protein (UniProt) level
  • Cross-checked (Default) (UniProt IDs: 14134, Interactions: 120882)
  • Standard (UniProt IDs: 14193, Interactions: 124871)
  • Unfiltered (UniProt IDs: 15725, Interactions: 191647)
  • Full (UniProt IDs: 15828, Interactions: 196828)
• Normalized at the Gene level
  • Cross-checked (Default) (Gene IDs:    14107, Interactions: 122429)
  • Standard (Gene IDs:    14167, Interactions: 126469)
  • Unfiltered (Gene IDs:    15652, Interactions: 193947)
  • Full (Gene IDs:    15756, Interactions: 199255)

 

PICKLE 1.1

PPI network

• Normalized at the Protein (UniProt) level
  • Standard (UniProt IDs: 9367, Interactions: 75965)