We are happy to inform you that the new release PICKLE 3.3 has been made available! This version includes the latest information of PPI and Biological databases for human and mouse species (for more details please check Downloads section).

We are happy to inform you that the new release PICKLE 3.2 has been made available! This version includes the latest information of PPI and Biological databases for human and mouse species (for more details please check Downloads section). Since this version, PICKLE integrates every other database included by IntAct.

A major update to version 3 has been made including PPIs for mouse species. More details can be found in our publication Dimitrakopoulos GN, Klapa MI, Moschonas NK. (2020). PICKLE 3.0: Enriching the human Meta-database with the mouse protein interactome extended via mouse-human orthology. Bioinformatics, https://doi.org/10.1093/bioinformatics/btaa1070..

We are happy to inform you that the new release PICKLE 2.5 has been made available! This version includes the latest information of PPI and Biological databases (for more details please check Downloads section). The default PICKLE network now contains 191113 interactions among 16418 UniProt IDs. Additionally, if you click on a protein, you will find new information, such as subcellular location, domains, related drugs and diseases.

PICKLE has been presented at the 14^th Conference of the Hellenic Society for Computational Biology and Bioinformatics as an oral presentation:
Dimitrakopoulos, G. N., Gioutlakis, A., Klapa, M. I., & Moschonas, N. K. (2019). Unraveling the way of expansion of the experimentally supported human protein interactome using the PICKLE meta-database. 14^th Conference of the Hellenic Society for Computational Biology and Bioinformatics 2019 (HSCBB19), December 08–10, 2019, Patras, Greece. https://sites.google.com/site/hscbb19/program

We are happy to inform you that the new release PICKLE 2.4 has been made available! This version includes the latest information of PPI and Biological databases (for more details please check Downloads section). The default PICKLE network now contains 189693 interactions among 16418 UniProt IDs.

PICKLE has been presented at the 52^nd Conference of the European Society of Human Genetics (ESHG), June 15–18, 2019, Gothenburg, Sweden as a poster presentation:
Dimitrakopoulos, G. N., Gioutlakis, A., Klapa, M. I., & Moschonas, N. K. (2019). Evaluating the expansion of the experimentally determined human protein interactome using the PICKLE meta-database. Abstracts from the 52nd European Society of Human Genetics (ESHG) Conference: Posters. European Journal of Human Genetics, 27, 1705-1705. https://doi.org/10.1038/s41431-019-0494-2

We are happy to inform you that the new release PICKLE 2.3 has been made available! This version includes the latest information of PPI and Biological databases (for more details please check Downloads section). The default PICKLE network now contains 178306 interactions among 15823 UniProt IDs.

PICKLE was presented at ELIXIR 2018 All Hands Meeting:
Gioutlakis A., Klapa M.I., Moschonas N.K. 2018. PICKLE 2.0: A human protein-protein interaction meta-database employing data integration via genetic information ontology. ELIXIR 2018 All Hands Meeting Berlin, June 4-7 2018.