News

PICKLE Database updated to version 3.1

12/12/2020
We are happy to inform you that the new release PICKLE 3.1 has been made available! This version includes the latest information of PPI and Biological databases (for more details please check Downloads section). This is a major update to version 3.0 including mouse PPIs. More details can be found in our publication Dimitrakopoulos GN, Klapa MI, Moschonas NK. (2020). PICKLE 3.0: Enriching the human Meta-database with the mouse protein interactome extended via mouse-human orthology. Bioinformatics, https://doi.org/10.1093/bioinformatics/btaa1070..

PICKLE Database updated to version 2.5

09/12/2019
We are happy to inform you that the new release PICKLE 2.5 has been made available! This version includes the latest information of PPI and Biological databases (for more details please check Downloads section). The default PICKLE network now contains 191113 interactions among 16418 UniProt IDs. Additionally, if you click on a protein, you will find new information, such as subcellular location, domains, related drugs and diseases.

PICKLE presented at HSCBB19 Conference

08/12/2019
PICKLE has been presented at the 14th Conference of the Hellenic Society for Computational Biology and Bioinformatics as an oral presentation:
Dimitrakopoulos, G. N., Gioutlakis, A., Klapa, M. I., & Moschonas, N. K. (2019). Unraveling the way of expansion of the experimentally supported human protein interactome using the PICKLE meta-database. 14th Conference of the Hellenic Society for Computational Biology and Bioinformatics 2019 (HSCBB19), December 08–10, 2019, Patras, Greece. https://sites.google.com/site/hscbb19/program

PICKLE Database updated to version 2.4

14/06/2019
We are happy to inform you that the new release PICKLE 2.4 has been made available! This version includes the latest information of PPI and Biological databases (for more details please check Downloads section). The default PICKLE network now contains 189693 interactions among 16418 UniProt IDs.

PICKLE presented at ESHG 2019 Conference

14/06/2019
PICKLE has been presented at the 52nd Conference of the European Society of Human Genetics (ESHG), June 15–18, 2019, Gothenburg, Sweden as a poster presentation:
Dimitrakopoulos, G. N., Gioutlakis, A., Klapa, M. I., & Moschonas, N. K. (2019). Evaluating the expansion of the experimentally determined human protein interactome using the PICKLE meta-database. Abstracts from the 52nd European Society of Human Genetics (ESHG) Conference: Posters. European Journal of Human Genetics, 27, 1705-1705. https://doi.org/10.1038/s41431-019-0494-2

New website design

01/12/2018

The new PICKLE 2.3 has come with an improved website! The updates include a modern theme and a new network visualization based on Cytoscape.js (using Javascript) instead of the deprecated CytoscapeWeb (using Flash). The new implementation now supports:

  • improved interactive network visualization
  • 6 network layouts
  • filtering based on our PPI Quality score
  • export as image functionality

PICKLE Database updated to version 2.3

31/10/2018
We are happy to inform you that the new release PICKLE 2.3 has been made available! This version includes the latest information of PPI and Biological databases (for more details please check Downloads section). The default PICKLE network now contains 178306 interactions among 15823 UniProt IDs.

PICKLE presented at All Hands Meeting of ELIXIR

07/06/2018
PICKLE was presented at ELIXIR 2018 All Hands Meeting:
Gioutlakis A., Klapa M.I., Moschonas N.K. 2018. PICKLE 2.0: A human protein-protein interaction meta-database employing data integration via genetic information ontology. ELIXIR 2018 All Hands Meeting Berlin, June 4-7 2018.